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Synthesis of pyrazoline derivatives from the 1,3-dipolar cycloadditions using α,β-unsaturated cyclohexanone derivatives
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Abstract
A series of 2-pyrazolines (3a-d) were obtained by reaction 1,3-dipolar cycloadditions of α,β-unsaturated cyclohexanone derivatives (2a-c) with hydrazine hydrate and 4-nitrophenylhydrazine in the presence of acetic acid and ethanol as solvents. The structures of the synthesized compounds were confirmed by spectroscopic methods; IR, 1H and 13C NMR.
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Article Details
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Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria.
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